Bullous eruptions in an infant - A rare case report

Background: Infantile vesiculobullous lesions are caused by infections, drugs, congenital and autoimmune disorders. Mastocytosis refers to over-proliferation and accumulation of tissue mast cells, encompassing a spectrum ranging from indolent cutaneous to malignant and systemic conditions. Bullous mastocytosis is a rare cutaneous form. Case characteristics: A male infant with recurring bullous lesions was confirmed to be mastocytosis on routine histopathology and special stains. Our patient was managed with antihistaminics and close monitoring with strict avoidance of triggering factors. Conclusion: Our patient responded very well to antihistaminics with complete subsidence of lesions without recurrence at 6 months follow-up. Hereby, we report this rare skin disorder encountered at our tertiary care centre. Bullous mastocytosis, though rare should be considered as one of the differentials in children with vesiculobullous lesions.